Warfarin Dosing Calculator

Clinical Note: Adjustments are based on the Percentage Change Method. For high INRs (>5.0), omit doses and check for signs of occult bleeding (bruising, hematuria, epistaxis).

When using a calculator, clinicians often refer to the following clinical standards (based on the ACCP Guidelines) for non-loading maintenance phases:

Current INRDose Adjustment RecommendationAction to Take
< 1.5Increase weekly dose by 15–20%Consider extra dose (booster)
1.5 – 1.9Increase weekly dose by 10–15%No booster usually needed
2.0 – 3.0No ChangeMaintain current schedule
3.1 – 3.9Decrease weekly dose by 10–15%Monitor INR in 1 week
4.0 – 4.9Hold 1 dose; Decrease weekly dose by 15%Close monitoring required
> 5.0Hold dose(s) until INR < 3.0Check for bleeding; Contact MD